| Description : |
This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
44 kDa |
| AA Sequence : |
MEPRRAAPGVPGWGSREAAGSASAA ELVYHLAGALGTELQDLARRFGPEA AAGLVPLVVRALELLEQAAVGPAPD SLQVSAQPAEQELRRLREENERLRR ELRAGPQEERALLRQLKEVTDRQRD ELRAHNRDLRQRGQETEALQEQLQR LLLVNAELRHKLAAMQTQLRAAQDR ERERQQPGEAATPQAKERARGQAGR PGHQHGQEPEWATAGAGAPGNPEDP AEAAQQLGRPSEAGQCRFSREEFEQ ILQERNELKAKVFLLKEELAYFQRE LLTDHRVPGLLLEAMKVAVRKQRKK IKAKMLGTPEEAESSEDEAGPWILL SDDKGDHPPPPESKIQSFFGLWYRG KAESSEDETSSPAPSKLGGEEEAQP QSPAPDPPCSALHEHLCLGASAAPE ATRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
