"RIN2" Related Products

Recombinant Human RIN2 Protein, MYC/DDK-tagged

Cat.No. : RIN2-1347H
Product Overview : Recombinant human RIN2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 100 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : Ras and Rab interactor 2 [ Homo sapiens ]
Official Symbol : RIN2
Synonyms : MACS; RASSF4
Gene ID : 54453
mRNA Refseq : NM_018993
Protein Refseq : NP_061866
MIM : 610222
UniProt ID : Q8WYP3

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