Recombinant Human RLBP1

• Cat.No.: RLBP1-26519TH
• Product Overview: Recombinant full length Human CRALBP with proprietary tag, 60.98kDa inclusive of tag.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: Non
• Protein Length: 317 amino acids
• Description: The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens.
• Molecular Weight: 60.980kDa inclusive of tags
• Tissue specificity: Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina.
• Biological activity: useful for Antibody Production and Protein Array
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.31% Glutathione, 0.79% Tris HClNote: Glutathione is reduced
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF
• Sequence Similarities: Contains 1 CRAL-TRIO domain.

Gene Information

• Gene Name: RLBP1 retinaldehyde binding protein 1 [ Homo sapiens ]
• Official Symbol: RLBP1
• Synonyms: RLBP1; retinaldehyde binding protein 1; retinaldehyde-binding protein 1; CRALBP
• Gene ID: 6017
• mRNA Refseq: NM_000326
• Protein Refseq: NP_000317
• MIM: 180090
• Uniprot ID: P12271
• Chromosome Location: 15q26.1
• Pathway: Vitamin A and carotenoid metabolism, organism-specific biosystem
• Function: 11-cis retinal binding; binding; retinol binding; transporter activity