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Recombinant Human RNH1 Protein, MYC/DDK-tagged, C13 and N15-labeled

Cat.No. : RNH1-173H
Product Overview : RNH1 MS Standard C13 and N15-labeled recombinant protein (NP_976318) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo. [supplied by OMIM, Jul 2010]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 50 kDa
AA Sequence : MSLDIQSLDIQCEELSDARWAELLP LLQQCQVVRLDDCGLTEARCKDISS ALRVNPALAELNLRSNELGDVGVHC VLQGLQTPSCKIQKLSLQNCCLTGA GCGVLSSTLRTLPTLQELHLSDNLL GDAGLQLLCEGLLDPQCRLEKLQLE YCSLSAASCEPLASVLRAKPDFKEL TVSNNDINEAGVHVLCQGLKDSPCQ LEALKLESCGVTSDNCRDLCGIVAS KASLRELALGSNKLGDVGMAELCPG LLHPSSRLRTLWIWECGITAKGCGD LCRVLRAKESLKELSLAGNELGDEG ARLLCETLLEPGCQLESLWVKSCSF TAACCSHFSSVLAQNRFLLELQISN NRLEDAGVRELCQGLGQPGSVLRVL WLADCDVSDSSCSSLAATLLANHSL RELDLSNNCLGDAGILQLVESVRQP GCLLEQLVLYDIYWSEEMEDRLQAL EKDKPSLRVISTRTRPLEQKLISEE DLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : RNH1 ribonuclease/angiogenin inhibitor 1 [ Homo sapiens (human) ]
Official Symbol : RNH1
Synonyms : RNH1; ribonuclease/angiogenin inhibitor 1; RAI; RNH; ribonuclease inhibitor; placental RNase inhibitor; placental ribonuclease inhibitor; testicular tissue protein Li 164
Gene ID : 6050
mRNA Refseq : NM_203384
Protein Refseq : NP_976318
MIM : 173320
UniProt ID : P13489

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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