Recombinant Human RNH1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human RNH1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : RNH1-1313H
Product Overview : RNH1 MS Standard C13 and N15-labeled recombinant protein (NP_976320) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 50 kDa
AA Sequence : Tags(s)X*A WTSRAWTSSV RS*ATLDGPS SSLCSSSAKW SGWTTVASRK HGARTSALHF ESTLHWQSST CAATSWAMSA CIACSRACRP PPARSRS*AS RTAA*RGPAA GSCPAHYAPC PPCRSCTSAT TSWGMRACSC SAKDSWTPSA AWKSCSWSIA ASRLPAASPW PPCSGPSRTS RSSRLATTTS MRLASVCCAR A*RTPPASWR RSSWRAAV*H QTTAGTCAAL WPPRPRCGSW PWAATSWVMW AWRSCAQGCS TPAPGSGPCG SGSVASLPRA AGICAVSSGP RRA*RSSAWP ATSWGMRVPD CCVRPCWNLA ASWSRCG*SP AASQPPAAPT SAQCWPRTGF SWSYR*ATTG WRMRACGSCA RAWASLALCC GCSGWPTAM* VTAAAAASPQ PCWPTTACVS WTSATTAWGT PASCSWWRAS GSRAASWSSW SCTTFTGLRR WRTGCRPWRR TSHP*GSSTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : RNH1 ribonuclease/angiogenin inhibitor 1 [ Homo sapiens (human) ]
Official Symbol : RNH1
Synonyms : RNH1; ribonuclease/angiogenin inhibitor 1; ribonuclease/angiogenin inhibitor, RNH; ribonuclease inhibitor; RAI; placental RNase inhibitor; placental ribonuclease inhibitor; RNH; MGC4569; MGC18200; MGC54054;
Gene ID : 6050
mRNA Refseq : NM_203386
Protein Refseq : NP_976320
MIM : 173320
UniProt ID : P13489

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