Recombinant Human ROBLD3 Protein, MYC/DDK-tagged

• Cat.No.: ROBLD3-162H
• Product Overview: Recombinant human ROBLD3 protein, fused to MYC/DDK-tag at C-terminal, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 13.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 [ Homo sapiens ]
• Official Symbol: LAMTOR2
• Synonyms: ENDAP; HSPC003; MAPBPIP; MAPKSP1AP; p14; Ragulator2; ROBLD3
• Gene ID: 28956
• mRNA Refseq: NM_001145264.1
• Protein Refseq: NP_001138736.1
• MIM: 610389
• UniProt ID: Q9Y2Q5C