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Recombinant Human ROCK1 protein, Flag-tagged, Biotinylated

Cat.No.: ROCK1-76H
Product Overview: Recombinant Human ROCK1, catalytic domain [1-477 amino acids of accession number NP_005397.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.
Source: Insect cell
Species: Human
Tag: Flag
Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Molecular Mass: 59 kDa
Purity: >90% as determined by SDS-PAGE and CBB staining
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: ROCK1 Rho-associated, coiled-coil containing protein kinase 1 [ Homo sapiens ]
Official Symbol: ROCK1
Synonyms: ROCK1; p160ROCK; p160-ROCK; Rho kinase; p160 ROCK-1; renal carcinoma antigen NY-REN-35; ROCK-I; P160ROCK; PRO0435
Gene ID: 6093
mRNA Refseq: NM_005406
Protein Refseq: NP_005397
MIM: 601702
UniProt ID: Q13464
Chromosome Location: 18q11.2
Pathway: Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem;
Function: ATP binding; GTP-Rho binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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