| Description : |
Sphingosine kinase catalyzes the formation of sphingosine 1 phosphate, a lipid cellular messenger. The protein encoded by this gene can bind to sphingosine kinase and to phosphatidylinositol 3-phosphate, suggesting a role in sphingosine 1 phophate signaling. The encoded protein can also bind to peroxiredoxin-3 and may help transport it to mitochondria. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
118.7 kDa |
| AA Sequence : |
MTSYRERSADLARFYTVTEPQRHPR GYTVYKVTARVVSRRNPEDVQEIIV WKRYSDFKKLHKELWQIHKNLFRHS ELFPPFAKGIVFGRFDETVIEERRQ CAEDLLQFSANIPALYNSKQLEDFF KGGIINDSSELIGPAEAHSDSLIDT FPECSTEGFSSDSDLVSLTVDVDSL AELDDGMASNQNSPIRTFGLNLSSD SSALGAVASDSEQSKTEEERESRSL FPGSLKPKLGKRDYLEKAGELIKLA LKKEEEDDYEAASDFYRKGVDLLLE GVQGESSPTRREAVKRRTAEYLMRA ESISSLYGKPQLDDVSQPPGSLSSR PLWNLRSPAEELKAFRVLGVIDKVL LVMDTRTEQTFILKGLRKSSEYSRN RKTIIPRCVPNMVCLHKYIISEESV FLVLQHAEGGKLWSYISKFLNRSPE ESFDIKEVKKPTLAKVHLQQPTSSP QDSSSFESRGSDGGSMLKALPLKSS LTPSSQDDSNQEDDGQDSSPKWPDS GSSSEEECTTSYLTLCNEYGQEKIE PGSLNEEPFMKTEGNGVDTKAIKSF PAHLAADSDSPSTQLRAHELKFFPN DDPEAVSSPRTSDSLSRSKNSPMEF FRIDSKDSASELLGLDFGEKLYSLK SEPLKPFFTLPDGDSASRSFNTSES KVEFKAQDTISRGSDDSVPVISFKD AAFDDVSGTDEGRPDLLVNLPGELE STREAAAMGPTKFTQTNIGIIENKL LEAPDVLCLRLSTEQCQAHEEKGIE ELSDPSGPKSYSITEKHYAQEDPRM LFVAAVDHSSSGDMSLLPSSDPKFQ GLGVVESAVTANNTEESLFRICSPL SGANEYIASTDTLKTEEVLLFTDQT DDLAKEEPTSLFQRDSETKGESGLV LEGDKEIHQIFEDLDKKLALASRFY IPEGCIQRWAAEMVVALDALHREGI VCRDLNPNNILLNDRGHIQLTYFSR WSEVEDSCDSDAIERMYCAPEVGAI TEETEACDWWSLGAVLFELLTGKTL VECHPAGINTHTTLNMPECVSEEAR SLIQQLLQFNPLERLGAGVAGVEDI KSHPFFTPVDWAELMRTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
