Description : |
The protein encoded by this intronless gene inhibits the expression of the solute carrier family 5 (sodium/glucose cotransporter), member 1 gene (SLC5A1) and downregulates exocytosis of the SLC5A1 protein. The encoded protein is sometimes found coating the trans-Golgi network and other times is localized to the nucleus, depending on the cell cycle stage. This protein also inhibits the expression of solute carrier family 22 (organic cation transporter), member 2 (SLC22A2). |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
66.6 kDa |
AA Sequence : |
MSSLPTSDGFNHPARSSGQSPDVGN PMSLARSVSASVCPIKPSDSDRIEP KAVKALKASAEFQLNSEKKEHLSLQ DLSDHASSADHAPTDQSPAMPMQNS SEEITVAGNLEKSAERSTQGLKFHL HTRQEASLSVTSTRMHEPQMFLGEK DWHPENQNLSQVSDPQQHEEPGNEQ YEVAQQKASHDQEYLCNIGDLELPE ERQQNQHKIVDLEATMKGNGLPQNV DPPSAKKSIPSSECSGCSNSETFME IDTAQQSLVTLLNSTGRQNANVKNI GALDLTLDNPLMEVETSKCNPSSEI LNDSISTQDLQPPETNVEIPGTNKE YGHYSSPSLCGSCQPSVESAEESCP SITAALKELHELLVVSSKPASENTS EEVICQSETIAEGQTSIKDLSERWT QNEHLTQNEQCPQVSFHQAISVSVE TEKLTGTSSDTGREAVENVNFRSLG DGLSTDKEGVPKSRESINKNRSVTV TSAKTSNQLHCTLGVEISPKLLAGE EDALNQTSEQTKSLSSNFILVKDLG QGIQNSVTDRPETRENVCPDASRPL LEYEPPTSHPSSSPAILPPLIFPAT DIDRILRAGFTLQEALGALHRVGGN ADLALLVLLAKNIVVPTTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |