| Description : |
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
79.6 kDa |
| AA Sequence : |
MADREGGCAAGRGRELEPELEPGPG PGSALEPGEEFEIVDRSQLPGPGDL RSATRPRAAEGWSAPILTLARRATG NLSASCGSALRAAAGLGGGDSGDGT ARAASKCQMMEERANLMHMMKLSIK VLLQSALSLGRSLDADHAPLQQFFV VMEHCLKHGLKVKKSFIGQNKSFFG PLELVEKLCPEASDIATSVRNLPEL KTAVGRGRAWLYLALMQKKLADYLK VLIDNKHLLSEFYEPEALMMEEEGM VIVGLLVGLNVLDANLCLKGEDLDS QVGVIDFSLYLKDVQDLDGGKEHER ITDVLDQKNYVEELNRHLSCTVGDL QTKIDGLEKTNSKLQEELSAATDRI CSLQEEQQQLREQNELIRERSEKSV EITKQDTKVELETYKQTRQGLDEMY SDVWKQLKEEKKVRLELEKELELQI GMKTEMEIAMKLLEKDTHEKQDTLV ALRQQLEEVKAINLQMFHKAQNAES SLQQKNEAITSFEGKTNQVMSSMKQ MEERLQHSERARQGAEERSHKLQQE LGGRIGALQLQLSQLHEQCSSLEKE LKSEKEQRQALQRELQHEKDTSSLL RMELQQVEGLKKELRELQDEKAELQ KICEEQEQALQEMGLHLSQSKLKME DIKEVNQALKGHAWLKDDEATHCRQ CEKEFSISRRKHHCRNCGHIFCNTC SSNELALPSYPKPVRVCDSCHTLLL QRCSSTASTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
