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Recombinant Human S100 Calcium Binding Protein A7

Cat.No. : S100A7-431H
Product Overview : Recombinant Human full length S100A7 (S100 calcium-binding protein A7, psoriasin) cloned from human cDNA was expressed inE.coli. The protein consists of the human S100A7 swissprot accession Q5SY67. MW = 22.9 kDa (dimer).
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Cat. No. : S100A7-431H
Description : Protein S100-A7 is a protein that in humans is encoded by the S100A7 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The protein functions as a prominent antimicrobial peptide mainly against E.coli.
Source : E.Coli.
Purity : > 95% by SDS-PAGE. The protein runs as a monomer giving a single band migrating at a molecular weight of <14 kDa.
Supplied As : 2mg/ml in Mes 30mM KCl 150 mM, pH 6.5. The concentration is calculated from the absorbance at 280nm (e280 = 4400 M-1 cm-1).
Characteristics : Under the above described conditions, to avoid precipitation, the product can be concentrated to a maximum of 0.4mM (dimer).
Storage : -20º C. The protein is stable at 4 ºC for at least 2 weeks and at 25 ºC for at least 1 day. After initial defrost, aliquot product into individual tubes and refreeze at -20º C. Avoid repeated freeze/defrost cycles.
Gene Name : S100A7 S100 calcium binding protein A7 [ Homo sapiens ]
Synonyms : S100A7; S100 calcium binding protein A7; PSOR1; S100A7c; S100A7; S100 calcium-binding protein A7 (psoriasin 1); S100 calcium binding protein A7 (psoriasin 1); psoriasin 1; OTTHUMP00000015328; OTTHUMP00000015327
Gene ID : 6278
mRNA Refseq : NM_002963
Protein Refseq : NP_002954
MIM : 600353
UniProt ID : P31151
Chromosome Location : 1q21
Function : calcium ion binding; protein binding; zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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