Recombinant Full Length Human S100A8 Protein, His-tagged

• Cat.No.: S100A8-3732H
• Product Overview: S100A8;S100 calcium binding protein A8;MRP8;Calgranulin A;CAGA;CFAG;P8;His-tagged;Human

Specification

• Species: Human
• Source: E. coli
• Tag: His
• Protein Length: 1-93 aa
• Description: S100A8 (S100 calcium binding protein A8), also known as MRP8 or Calgranulin A, is a calcium- and zinc-binding EF-hand protein predominantly expressed in myeloid cells including neutrophils and monocytes. It forms a heterodimer complex with S100A9 (Calprotectin) and plays critical roles in inflammatory responses, antimicrobial defense, cytoskeleton rearrangement, and arachidonic acid metabolism regulation.
• Form: Liquid
• Molecular Mass: 12 kDa (calculated)
• AASequence: MKHHHHHHASMLTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHKE
• Endotoxin: <1.0 EU/ug (by LAL)
• Purity: >90% (by SDS-PAGE)
• Storage: Store under sterile conditions at -20°C to -80°C, aliquot, avoid repeated freeze-thaw cycles
• Concentration: 1 mg/ml (by BCA)
• Storage Buffer: Sterile PBS, pH7.4

Gene Information

• Gene Name: S100A8
• Official Symbol: NM_002964.5
• Synonyms: NP_002955.2
• Gene ID: https://www.ncbi.nlm.nih.gov/protein/NP_002955.2
• mRNA Refseq: https://www.uniprot.org/uniprotkb/P05109
• Protein Refseq: https://www.ncbi.nlm.nih.gov/gene/6279
• MIM: https://www.omim.org/entry/123885