Recombinant Human SALa Protein, His&SUMO-tagged

• Cat.No.: SALa-2671H
• Product Overview: Recombinant Human SALa Protein (Ser214-Lys241*3) with N-His&SUMO tag was expressed in E. coli.

Specification

• Description: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.
• Source: E. coli
• Species: Human
• Tag: N-His&SUMO
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 21.5 kDa
  Accurate Molecular Mass: 29 kDa
• Protein length: Ser214-Lys241*3
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
• Official Symbol: SALa
• Synonyms: Salusin Alpha; SALa

Gene Information

• Official Symbol: SALa
• Synonyms: Salusin Alpha; SALa