Recombinant Human SASS6 Protein (1-490), N-GST-tagged

• Cat.No.: SASS6-2515H
• Product Overview: Recombinant human SASS6 full-length ORF ( AAI01027.1, 1 a.a.-490 a.a.) recombinant protein with GST-tag at N-terminal was expressed in Wheat Germ (in vitro).

Specification

• Description: The protein encoded by this gene is a central component of centrioles and is necessary for their duplication and function. Centrioles adopt a cartwheel-shaped structure, with the encoded protein forming the hub and spokes inside a microtubule cylinder. Defects in this gene are a cause of autosomal recessive primary microcephaly.
• Source: Wheat Germ (in vitro)
• Species: Human
• Tag: N-GST
• Molecular Mass: 81.7 kDa
• Protein Length: 1-490
• AA Sequence: MQSLDDATKQLDFTRKTLAEKKQEL DKLRNEWASHTAALTNKHSQELTNE KEKALQAQVQYQQQHEQQKKDLEIL HQQNIHQLQNRLSELEVANKDLTER KYKGDSTIRELKAKLSGVEEELQRT KQEVLSLRRENSTLDVECHEKEKHV NQLQTKVAVLEQEIKDKDQLVLRTK EAFDTIQEQKVVLEENGEKNQVQLG KLEATIKSLSAELLKANEIIKKLQG DLKTLMGKLKLKNTVTIQQEKLLAE KEEKLQKEQKELQDVGQSLRIKEQE VCKLQEQLEATVKKLEESKQLLKNN EKLITWLNKELNENQLVRKQDVLGP STTPPAHSSSNTIRSGISPNLNVVD GRLTYPTCGIGYPVSSAFAFQNTFP HSISAKNTSHPGSGTKVQFNLQFTK PNASLGDVQSGATISMPCSTDKENG ENVGLESKYLKKREDSIPLRGLSQN LFSNSDHQRDGTLGALHTSSKPTAL PSASSAYFPGQLPNS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: SASS6 SAS-6 centriolar assembly protein [ Homo sapiens (human) ]
• Official Symbol: SASS6
• Synonyms: SASS6; SAS-6 centriolar assembly protein; SAS6; SAS-6; MCPH14; spindle assembly abnormal protein 6 homolog
• Gene ID: 163786
• mRNA Refseq: NM_194292
• Protein Refseq: NP_919268
• MIM: 609321
• UniProt ID: Q6UVJ0