Recombinant Human SCCA2

Species :	Human
Source :	E.coli
Tag :	Non
Description :	Squamous cell carcinoma antigen (SCCA), a member of the serine protease inhibitor (serpin) family, is a subfraction of the tumor associated antigen TA-4, is a glycoprotein, with a molecular weight between 42 to 48 kDa. SCCA2 is a serological marker for squamous cell carcinomas (SCC). Elevated serum levels are correlated with the clinical stage of the disease.Schneider et al. demonstrated that 18q21.3 contains a cluster of serine proteinase inhibitors, or serpins, including a tandem duplication of the squamous cell carcinoma antigen (SCCA) gene and 2 other members of the ovalbumin family of serine proteinase inhibitors, plasminogen activator inhibitor type 2 and maspin (protease inhibitor-5). Schneider et al. presented evidence that the neutral and acidic forms of SCCA are encoded by SCCA1 and SCCA2, respectively.
Form :	The protein solution is in 0.05M phosphate buffer containing 0.15M NaCl and 0.09% NaN3 pH 7.5. Filtered through a 0.4μM membrane.
Molecular Mass :	9.3kDa
Endotoxin :	< 1.0 eu per μg of the protein as determined by the LAL method.
Purity :	>95 % as determined by SDS-PAGE
Applications :	Western blotting, ELISA
Storage :	Store it under sterile conditions at -20℃ to -121℃ upon receiving.Recommend to aliquot the protein into smaller quantities for optimal storage.