Description : |
The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
75.3 kDa |
AA Sequence : |
MSNVTLRKMSPTGNEMKSTTQGTTR KQQDFHEVNKRRTFLQDNSWIKKRP EEEKDENYGRVVLNRHNSHDALDRK VNERDVPKATISRYSSDDTLDRISD RNDAAKTYKANTLDNQLTNRSMSVF RSLEVTKLQPGGSLNANTSNTIAST SATTPVKKKRQSWFPPPPPGYNASS STGTRRREPGVHPPIPPKPSSPVSS TNQLRQDNRQIHPPKPGVYTETNRS AERNISEELDNLIKMNKSLNRNQGL DSLFRANPKVEEREKRAKSLESLIY MSTRTDKDGKGIQSLGSPIKVNQRT DKNEKGRQNLESVAKVNARMNKTSR RSEDLDNATEVNPKGHENTTGKKDL DGLIKVDPETNKNITRGQSLDNLIK VTPEVKRSNQGSKDLNNFIKVYPGT EKSTEGGQSLDSLIKVTPERNRTNQ GNQDLENLIKVIPSANKSSEQGLDE HINVSPKAVKNTDGKQDLDKLIKVN PEIFTNNQRNQDLANLIKVNPAVIR NNQSQDLDNLIKVKPSALRNTNRDQ NLENLIEVNSHVSENKNGSSNTGAK QAGPQDTVVYTRTYVENSKSPKDGY QENISGKYIQTVYSTSDRSVIERDM CTYCRKPLGVETKMILDELQICCHS TCFKCEICKQPLENLQAGDSIWIYR QTIHCEPCYSKIMAKWIPTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |