Recombinant Human SDC1 Protein, His-tagged

• Cat.No.: SDC1-15H
• Product Overview: Recombinant human SDC1 (18-254aa) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Syndecan-1 precursor, also known as SDC1, is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. SDC1 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Liquid
• Molecular Mass: 27 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMGSHM QPALPQIVATNLPPEDQDGSGDDSD NFSGSGAGALQDITLSQQTPSTWKD TQLLTAIPTSPEPTGLEATAASTST LPAGEGPKEGEAVVLPEVEPGLTAR EQEATPRPRETTQLPTTHQASTTTA TTAQEPATSHPHRDMQPGHHETSTP AGPSQADLHTPHTEDGGPSATERAA EDGASSQLPAAEGSGEQDFTFETSG ENTAVVAVEPDRRNQSPVDQGATGA SQGLLDRKEVLG
• Purity: > 90% by SDS - PAGE
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/mL
• Storage Buffer: In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Gene Information

• Gene Name: SDC1
• Official Symbol: SDC1 syndecan 1 [ Homo sapiens (human) ]
• Synonyms: SDC1; syndecan 1; CD138; SDC; SYND1; syndecan; syndecan-1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan proteoglycan 1
• Gene ID: 6382
• mRNA Refseq: NM_002997
• Protein Refseq: NP_002988
• MIM: 186355
• UniProt ID: P18827

Reviews

10/14/2023

Each customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.

07/22/2023

High quality product at a good price, a satisfactory shopping experience.

07/13/2023

The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.

Q&As

In which tissues is SDC1 mainly expressed?

SDC1 is predominantly expressed in epithelial tissues.

How is SDC1 linked to the ZEB1 transcription factor?

The ZEB1 transcription factor acts on SDC1 and represses its expression.

How does SDC1 relate to the expression of the tight junction protein E-cadherin?

SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.

What are the effects of inhibiting SDC1 expression?

Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.

What diseases is SDC1 involved in?

SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.

Where is SDC1 located?

SDC1 is localized to the cell membrane.

What biological processes is SDC1 involved in?

SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.