Recombinant Human SDC1 Protein, His-tagged

Cat.No. : SDC1-15H
Product Overview : Recombinant human SDC1 (18-254aa) protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Description : Syndecan-1 precursor, also known as SDC1, is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. SDC1 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia.
Source : E.coli
Species : Human
Tag : His
Form : Liquid
Molecular Mass : 27 kDa
AA Sequence : MGSSHHHHHHSSGLVPRGSHMGSHM QPALPQIVATNLPPEDQDGSGDDSD NFSGSGAGALQDITLSQQTPSTWKD TQLLTAIPTSPEPTGLEATAASTST LPAGEGPKEGEAVVLPEVEPGLTAR EQEATPRPRETTQLPTTHQASTTTA TTAQEPATSHPHRDMQPGHHETSTP AGPSQADLHTPHTEDGGPSATERAA EDGASSQLPAAEGSGEQDFTFETSG ENTAVVAVEPDRRNQSPVDQGATGA SQGLLDRKEVLG
Purity : > 90% by SDS - PAGE
Notes : For research use only. This product is not intended or approved for human, diagnostics or veterinary use
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/mL
Storage Buffer : In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
SDS-PAGE:
Gene Name : SDC1
Official Symbol : SDC1 syndecan 1 [ Homo sapiens (human) ]
Synonyms : SDC1; syndecan 1; CD138; SDC; SYND1; syndecan; syndecan-1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan proteoglycan 1
Gene ID : 6382
mRNA Refseq : NM_002997
Protein Refseq : NP_002988
MIM : 186355
UniProt ID : P18827

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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In which tissues is SDC1 mainly expressed? 05/14/2022

SDC1 is predominantly expressed in epithelial tissues.

How is SDC1 linked to the ZEB1 transcription factor? 05/04/2022

The ZEB1 transcription factor acts on SDC1 and represses its expression.

How does SDC1 relate to the expression of the tight junction protein E-cadherin? 03/05/2022

SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.

What are the effects of inhibiting SDC1 expression? 11/23/2021

Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.

What diseases is SDC1 involved in? 09/17/2021

SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.

Where is SDC1 located? 03/31/2021

SDC1 is localized to the cell membrane.

What biological processes is SDC1 involved in? 11/20/2020

SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.

Customer Reviews (3)

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10/14/2023

    Each customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.

    07/22/2023

      High quality product at a good price, a satisfactory shopping experience.

      07/13/2023

        The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.

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