Recombinant Human SDC1 Protein, His-tagged

Cat.No. : SDC1-452H
Product Overview : Recombinant human SDC1 protein with His tag was expressed in HEK293.
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Description : The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Source : HEK293
Species : Human
Tag : His
Form : Lyophilized
Molecular Mass : 24.7 kDa
Protein Length : 310
AA Sequence : MRRAALWLWLCALALSLQPALPQIV ATNLPPEDQDGSGDDSDNFSGSGAG ALQDITLSQQTPSTWKDTQLLTAIP TSPEPTGLEATAASTSTLPAGEGPK EGEAVVLPEVEPGLTAREQEATPRP RETTQLPTTHLASTTTATTAQEPAT SHPHRDMQPGHHETSTPAGPSQADL HTPHTEDGGPSATERAAEDGASSQL PAAEGSGEQDFTFETSGENTAVVAV EPDRRNQSPVDQGATGASQGLLDRK EVLGGVIAGGLVGLIFAVCLVGFML YRMKKKDEGSYSLEEPKQANGGAYQ KPTKQEEFYA
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : SDC1 syndecan 1 [ Homo sapiens (human) ]
Official Symbol : SDC1
Synonyms : SDC1; syndecan 1; SDC; syndecan-1; CD138; SYND1; syndecan; syndecan proteoglycan 1; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor;
Gene ID : 6382
mRNA Refseq : NM_001006946
Protein Refseq : NP_001006947
MIM : 186355
UniProt ID : P18827

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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In which tissues is SDC1 mainly expressed? 05/14/2022

SDC1 is predominantly expressed in epithelial tissues.

How is SDC1 linked to the ZEB1 transcription factor? 05/04/2022

The ZEB1 transcription factor acts on SDC1 and represses its expression.

How does SDC1 relate to the expression of the tight junction protein E-cadherin? 03/05/2022

SDC1 protein expression was positively correlated with E-cadherin protein expression and acted synergistically.

What are the effects of inhibiting SDC1 expression? 11/23/2021

Inhibition of SDC1 expression promotes tumor growth, invasion and metastasis.

What diseases is SDC1 involved in? 09/17/2021

SDC1 is involved in the study of diseases such as liver cancer, colon cancer and breast cancer.

Where is SDC1 located? 03/31/2021

SDC1 is localized to the cell membrane.

What biological processes is SDC1 involved in? 11/20/2020

SDC1 is involved in biological processes such as cell proliferation, differentiation, and adhesion.

Customer Reviews (3)

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10/14/2023

    Each customer has a dedicated customer service to provide one-on-one, specialized service that solved the problem in my experiment.

    07/22/2023

      High quality product at a good price, a satisfactory shopping experience.

      07/13/2023

        The product brochure is very detailed and has comprehensive basic information about the SDC1 protein.

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