| Description : |
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein is thought to be a cargo-binding component of the COPII vesicle, and is thought to be involved in the transport of secretory proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in this gene have been associated with neural tube defects, and are thought to be a result of a disruption in interactions with the protein encoded by the VANGL planar cell polarity protein 2 (VANGL2) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
133.4 kDa |
| AA Sequence : |
MSAPAGSSHPAASARIPPKFGGAAV SGAAAPAGPGAGPAPHQQNGPAQNQ MQVPSGYGLHHQNYIAPSGHYSQGP GKMTSLPLDTQCGDYYSALYTVPTQ NVTPNTVNQQPGAQQLYSRGPPAPH IVGSTLGSFQGAASSASHLHTSASQ PYSSFVNHYNSPAMYSASSSVASQG FPSTCGHYAMSTVSNAAYPSVSYPS LPAGDTYGQMFTSQNAPTVRPVKDN SFSGQNTAISHPSPLPPLPSQQHHQ QQSLSGYSTLTWSSPGLPSTQDNLI RNHTGSLAVANNNPTITVADSLSCP VMQNVQPPKSSPVVSTVLSGSSGSS STRTPPTANHPVEPVTSVTQPSELL QQKGVDSSSTTSSASPMPNSYDALE GGSYPDMLSSSASSPAPDPAPEPDP ASAPAPASAPAPVVPQPSKMAKPFG YGYPTLQPGYQNATAPLISGVQPSN PVYSGFQQYPQQYPGVNQLSSSIGG LSLQSSPQPESLRPVNLTQERNILP MTPVWAPVPNLNADLKKLNCSPDSF RCTLTNIPQTQALLNKAKLPLGLLL HPFRDLTQLPVITSNTIVRCRSCRT YINPFVSFIDQRRWKCNLCYRVNDV PEEFMYNPLTRSYGEPHKRPEVQNS TVEFIASSDYMLRPPQPAVYLFVLD VSHNAVEAGYLTILCQSLLENLDKL PGDSRTRIGFMTFDSTIHFYNLQEG LSQPQMLIVSDIDDVFLPTPDSLLV NLYESKELIKDLLNALPNMFTNTRE THSALGPALQAAFKLMSPTGGRVSV FQTQLPSLGAGLLQSREDPNQRSST KVVQHLGPATDFYKKLALDCSGQQT AVDLFLLSSQYSDLASLACMSKYSA GCIYYYPSFHYTHNPSQAEKLQKDL KRYLTRKIGFEAVMRIRCTKGLSMH TFHGNFFVRSTDLLSLANINPDAGF AVQLSIEESLTDTSLVCFQTALLYT SSKGERRIRVHTLCLPVVSSLADVY AGVDVQAAICLLANMAVDRSVSSSL SDARDALVNAVVDSLSAYGSTVSNL QHSALMAPSSLKLFPLYVLALLKQK AFRTGTSTRLDDRVYAMCQIKSQPL VHLMKMIHPNLYRIDRLTDEGAVHV NDRIVPQPPLQKLSAEKLTREGAFL MDCGSVFYIWVGKGCDNNFIEDVLG YTNFASIPQKMTHLPELDTLSSERA RSFITWLRDSRPLSPILHIVKDESP AKAEFFQHLIEDRTEAAFSYYEFLL HVQQQICKTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
