Recombinant Human SEH1L Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SEH1L-6684H
• Product Overview: SEH1L MS Standard C13 and N15-labeled recombinant protein (NP_112493) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is part of a nuclear pore complex, Nup107-160. This protein contains WD repeats and shares 34% amino acid identity with yeast Seh1 and 30% identity with yeast Sec13. All constituents of the Nup107-160 complex, including this protein, specifically localize to kinetochores in mitosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.6 kDa
• AA Sequence: MFVARSIAADHKDLIHDVSFDFHGR RMATCSSDQSVKVWDKSESGDWHCT ASWKTHSGSVWRVTWAHPEFGQVLA SCSFDRTAAVWEEIVGESNDKLRGQ SHWVKRTTLVDSRTSVTDVKFAPKH MGLMLATCSADGIVRIYEAPDVMNL SQWSLQHEISCKLSCSCISWNPSSS RAHSPMIAVGSDDSSPNAMAKVQIF EYNENTRKYAKAETLMTVTDPVHDI AFAPNLGRSFHILAIATKDVRIFTL KPVRKELTSSGGPTKFEIHIVAQFD NHNSQVWRVSWNITGTVLASSGDDG CVRLWKANYMDNWKCTGILKGNGSP VNGSSQQGTSNPSLGSTIPSLQNSL NGSSAGRKHSTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SEH1L SEH1 like nucleoporin [ Homo sapiens (human) ]
• Official Symbol: SEH1L
• Synonyms: SEH1L; SEH1 like nucleoporin; Seh1; SEH1A; SEH1B; SEC13L; nucleoporin SEH1; GATOR complex protein SEH1; SEC13-like protein; nup107-160 subcomplex subunit SEH1; sec13 like protein
• Gene ID: 81929
• mRNA Refseq: NM_031216
• Protein Refseq: NP_112493
• MIM: 609263
• UniProt ID: Q96EE3