Recombinant Human SELE protein, His-Avi-tagged, Biotinylated

• Cat.No.: SELE-581HB
• Product Overview: Biotinylated Human E-selectin Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Trp22-Pro556.

Specification

• Description: E-Selectin (Endothelial Leukocyte Adhesion Molecule-1, ELAM-1, CD62E), a member of the Selectin family, is a 107-115 kDa cell surface glycoprotein. It is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha.E-selectin mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 61.6 kDa. Due to glycosylation, the protein migrates to 80-90kDa based on Bis-Tris PAGE result.
• Protein length: Trp22-Pro556
• Endotoxin: Less than 0.1 EU per μg by the LAL method.
• Purity: >95% as determined by Tris-Bis PAGE; >95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: SELE
• Official Symbol: SELE
• Synonyms: CD62 antigen-like family member E; CD62E antigen; CD62E; ELAM; ELAM1; ELAM-1; ELAM1E-selectin; endothelial adhesion molecule 1; Endothelial leukocyte adhesion molecule 1; ESEL; E-Selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2; Leukocyte-endothelial cell adhesion molecule 2; SELE; selectin E
• Gene ID: 6401
• mRNA Refseq: NM_000450.2
• Protein Refseq: NP_000441.2
• MIM: 131210
• UniProt ID: P16581