| Description : |
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
66.66 kDa |
| AA Sequence : |
MIASQFLSALTLVLLIKESGAWSYN TSTEAMTYDEASAYCQQRYTHLVAI QNKEEIEYLNSILSYSPSYYWIGIR KVNNVWVWVGTQKPLTEEAKNWAPG EPNNRQKDEDCVEIYIKREKDVGMW NDERCSKKKLALCYTAACTNTSCSG HGECVETINNYTCKCDPGFSGLKCE QIVNCTALESPEHGSLVCSHPLGNF SYNSSCSISCDRGYLPSSMETMQCM SSGEWSAPIPACNVVECDAVTNPAN GFVECFQNPGSFPWNTTCTFDCEEG FELMGAQSLQCTSSGNWDNEKPTCK AVTCRAVRQPQNGSVRCSHSPAGEF TFKSSCNFTCEEGFMLQGPAQVECT TQGQWTQQIPVCEAFQCTALSNPER GYMNCLPSASGSFRYGSSCEFSCEQ GFVLKGSKRLQCGPTGEWDNEKPTC EAVRCDAVHQPPKGLVRCAHSPIGE FTYKSSCAFSCEEGFELHGSTQLEC TSQGQWTEEVPSCQVVKCSSLAVPG KINMSCSGEPVFGTVCKFACPEGWT LNGSAARTCGATGHWSGLLPTCEAP TESNIPLVAGLSAAGLSLLTLAPFL LWLRKCLRKAKKFVPASSCQSLESD GSYQKPSYILTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
