Recombinant Human SEMA7A Protein, His&Fc tagged

• Cat.No.: SEMA7A-30H
• Product Overview: Recombinant human SEMA7A (45-648 aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Fc&His
• Protein Length: 45-648 aa
• Description: This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
• Form: Liquid
• AASequence: QGHLRSGPRIFAVWKGHVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSCLDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALA
• Molecular Mass: 95.7 kDa
• Endotoxin: < 1 EU/μg by LAL
• Purity: > 90% by SDS-PAGE
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
• Concentration: 0.25 mg/mL (determined by absorbance at 280nm)

Gene Information

• Gene ID: 8482
• Gene Name: SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) [ Homo sapiens (human) ]
• Official Symbol: 8482
• Synonyms: SEMA7A; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group), SEMAL; semaphorin-7A; CD108; H Sema K1; H Sema L; John Milton Hagen blood group; sema L; sema K1; semaphorin L; semaphorin-L; semaphorin K1; semaphorin-K1; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); JMH; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1; MGC126692; MGC126696
• mRNA Refseq: NM_003612
• Official Symbol 2: SEMA7A
• Gene ID 2: 8482
• Gene Name 2: SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) [ Homo sapiens (human) ]
• mRNA Refseq 2: NM_003612
• Protein Refseq 2: NP_003603
• MIM 2: 607961
• UniProt ID 2: O75326