Recombinant Human SEPTIN4 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human SEPTIN4 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : SEPTIN4-4441H
Product Overview : SEPT4 MS Standard C13 and N15-labeled recombinant protein (NP_004565) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 54.9 kDa
AA Sequence : MDRSLGWQGN SVPEDRTEAG IKRFLEDTTD DGELSKFVKD FSGNASCHPP EAKTWASRPQ VPEPRPQAPD LYDDDLEFRP PSRPQSSDNQ QYFCAPAPLS PSARPRSPWG KLDPYDSSED DKEYVGFATL PNQVHRKSVK KGFDFTLMVA GESGLGKSTL VNSLFLTDLY RDRKLLGAEE RIMQTVEITK HAVDIEEKGV RLRLTIVDTP GFGDAVNNTE CWKPVAEYID QQFEQYFRDE SGLNRKNIQD NRVHCCLYFI SPFGHGLRPL DVEFMKALHQ RVNIVPILAK ADTLTPPEVD HKKRKIREEI EHFGIKIYQF PDCDSDEDED FKLQDQALKE SIPFAVIGSN TVVEARGRRV RGRLYPWGIV EVENPGHCDF VKLRTMLVRT HMQDLKDVTR ETHYENYRAQ CIQSMTRLVV KERNRNKLTR ESGTDFPIPA VPPGTDPETE KLIREKDEEL RRMQEMLHKI QKQMKENYTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : SEPTIN4 septin 4 [ Homo sapiens (human) ]
Official Symbol : SEPTIN4
Synonyms : SEPTIN4; septin 4; H5; ARTS; MART; SEP4; CE5B3; SEPT4; PNUTL2; hucep-7; BRADEION; C17orf47; hCDCREL-2; septin-4; CE5B3 beta; apoptosis-related protein in the TGF-beta signaling pathway; bradeion beta; brain protein H5; cell division control-related protein 2; cerebral protein 7; peanut-like protein 2; septin-M; uncharacterized protein C17orf47
Gene ID : 5414
mRNA Refseq : NM_004574
Protein Refseq : NP_004565
MIM : 603696
UniProt ID : O43236
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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