| Description : |
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
54.9 kDa |
| AA Sequence : |
MDRSLGWQGNSVPEDRTEAGIKRFL EDTTDDGELSKFVKDFSGNASCHPP EAKTWASRPQVPEPRPQAPDLYDDD LEFRPPSRPQSSDNQQYFCAPAPLS PSARPRSPWGKLDPYDSSEDDKEYV GFATLPNQVHRKSVKKGFDFTLMVA GESGLGKSTLVNSLFLTDLYRDRKL LGAEERIMQTVEITKHAVDIEEKGV RLRLTIVDTPGFGDAVNNTECWKPV AEYIDQQFEQYFRDESGLNRKNIQD NRVHCCLYFISPFGHGLRPLDVEFM KALHQRVNIVPILAKADTLTPPEVD HKKRKIREEIEHFGIKIYQFPDCDS DEDEDFKLQDQALKESIPFAVIGSN TVVEARGRRVRGRLYPWGIVEVENP GHCDFVKLRTMLVRTHMQDLKDVTR ETHYENYRAQCIQSMTRLVVKERNR NKLTRESGTDFPIPAVPPGTDPETE KLIREKDEELRRMQEMLHKIQKQMK ENYTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
