Recombinant Human Serine/Threonine/Tyrosine Interacting Protein, His-tagged

• Cat.No.: STYX-1935H
• Product Overview: Recombinant human STYXprotein, fused to His-tag at N-terminus, was expressed in E.coli and purifiedby using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: STYX, also known as serine/threonine/tyrosine-interactingprotein, belongs to the protein-tyrosine phosphatase family. It contains aGly residue instead of a conserved Cys residue in the dsPTPase catalytic loopwhich renders it catalytically inactive as a phosphatase. The binding pocketis however sufficiently preserved to bind phosphorylated substrates, andmaybe protect them from phosphatases. It seems to play a role inspermiogenesis.
• Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 30% glycerol 1mM DTT,0.1M NaCl.
• Molecular Weight: 28.0 kDa(247aa) confirmedby MALDI-TOF.
• Purity: > 85% by SDS - PAGE.
• Concentration: 0.25 mg/ml(determined by Bradford assay).
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMEDVKL EFPSLPQCKE DAEEWTYPMR REMQEILPGL FLGPYSSAMK SKLPVLQKHGITHIICIRQN IEANFIKPNF QQLFRYLVLD IADNPVENII RFFPMTKEFI DGSLQMGGKV LVHGNAGISRSAAFVIAYIM ETFGMKYRDA FAYVQERRFC INPNAGFVHQ LQEYEAIYLA KLTIQMMSPLQIERSLSVHS GTTGSLKRTH EEEDDFGTMQ VATAQNG
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: STYX

Gene Information

• Gene Name: STYX serine/threonine/tyrosineinteracting protein [ Homo sapiens ]
• Synonyms: STYX;serine/threonine/tyrosine interacting protein; serine/threonine/tyrosine-interactingprotein; protein tyrosine phosphatase-like protein
• Gene ID: 6815
• mRNA Refseq: NM_001130701
• Protein Refseq: NP_001124173
• UniProt ID: Q8WUJ0
• Chromosome Location: 14q22.1
• Function: hydrolase activity;NOT protein tyrosine/serine/threonine phosphatase activity