"SETD2" Related Products


Recombinant Human SETD2 protein, GST-tagged

Cat.No.: SETD2-260H
Product Overview: Recombinant Human SETD2(1345-1711 aa) fused with GST tag at N-terminal was expressed in E. coli.
Description: SETD2 is a SET-domain containing histone methyltransferase, catalyzing the trimethylation of histone H3 at lysine 36. SETD2 is a candidate tumor suppressor protein and mutated in clear cell renal cell carcinoma.
Source: E. coli
Species: Human
Tag : GST
Form: In 50mM Tris pH 7.3, 300 mM NaCl, 4mM DTT, 1µM ZnCl2 and 25% glycerol.
Molecular Mass: 68 kDa
Applications: SETD2, Recombinant Human GST-tagged is useful for histone H3 methylation experiments, enzyme kinetics and inhibitor screening. Use of 0.5 - 2.5 µg SETD2 per reaction with nucleosomes or recombinant histone H3 as a substrate is recommended.
Storage: Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration: 1 µg/µl
Gene Name: SETD2 SET domain containing 2 [ Homo sapiens ]
Official Symbol: SETD2
Synonyms: SETD2; SET domain containing 2; histone-lysine N-methyltransferase SETD2; FLJ23184; HIF 1; HYPB; KIAA1732; KMT3A; huntingtin yeast partner B; lysine N-methyltransferase 3A; huntingtin interacting protein 1; huntingtin-interacting protein B; SET2; HIF-1; HIP-1; HBP231; HSPC069; p231HBP; FLJ16420; FLJ22472; FLJ45883; FLJ46217;
Gene ID: 29072
mRNA Refseq: NM_014159
Protein Refseq: NP_054878
MIM: 612778
UniProt ID: Q9BYW2
Chromosome Location: 3p21.31
Pathway: Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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