Recombinant Human SETMAR Protein, MYC/DDK-tagged

• Cat.No.: SETMAR-1121H
• Product Overview: Recombinant human SETMAR protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 77.9 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SETMAR SET domain and mariner transposase fusion gene [ Homo sapiens ]
• Official Symbol: SETMAR
• Synonyms: Mar1; METNASE
• Gene ID: 6419
• mRNA Refseq: NM_001243723
• Protein Refseq: NP_001230652
• MIM: 609834
• UniProt ID: Q53H47