Recombinant Human SETMAR Protein, MYC/DDK-tagged


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Recombinant Human SETMAR Protein, MYC/DDK-tagged

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Cat.No. : SETMAR-1121H
Product Overview : Recombinant human SETMAR protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013].
Source : HEK293
Species : Human
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 77.9 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : SETMAR SET domain and mariner transposase fusion gene [ Homo sapiens ]
Official Symbol : SETMAR
Synonyms : Mar1; METNASE
Gene ID : 6419
mRNA Refseq : NM_001243723
Protein Refseq : NP_001230652
MIM : 609834
UniProt ID : Q53H47

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