Recombinant Human SF3B6 Protein, HIS-tagged

• Cat.No.: SF3B6-183H
• Product Overview: Recombinant Human SF3B6 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 100 mM Arg. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 14.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SF3B6 splicing factor 3b subunit 6 [ Homo sapiens (human) ]
• Official Symbol: SF3B6
• Synonyms: P14; Ht006; SAP14; SAP14a; SF3B14; CGI-110; HSPC175; SF3B14a; SF3B6
• Gene ID: 51639
• mRNA Refseq: NM_016047
• Protein Refseq: NP_057131
• MIM: 607835
• UniProt ID: Q9Y3B4