Recombinant Human SFTPB Protein (201-279 aa)

• Cat.No.: SFTPB-2223H
• Product Overview: Recombinant Human SFTPB Protein (201-279 aa) is produced by Yeast expression system. Research Area: Cell Biology. Protein Description: Full Length of Mature Protein.

Specification

• Description: Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
• Source: Yeast
• Species: Human
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 8.7 kDa
• Protein length: 201-279 aa
• AA Sequence: FPIPLPYCWLCRALIKRIQAMIPKG ALAVAVAQVCRVVPLVAGGICQCLA ERYSVILLDTLLGRMLPQLVCRLVL RCSM
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: SFTPB surfactant protein B [ Homo sapiens ]
• Official Symbol: SFTPB
• Synonyms: SFTPB; surfactant protein B; SP B; 6 kDa protein; SP-B; PSP-B; SFTB3; SFTP3; SMDP1
• Gene ID: 6439
• mRNA Refseq: NM_000542
• Protein Refseq: NP_000533
• MIM: 178640
• UniProt ID: P07988

Reviews

03/04/2022

Its outstanding performance, coupled with its ease of use, has enhanced the overall efficiency and accuracy of my research.

05/31/2020

The SFTPB Protein has greatly contributed to the success of my experiments, providing reliable and robust data.

07/22/2016

I highly recommend the SFTPB Protein to researchers seeking a reliable and high-performing protein for their ELISA assays and protein electron microscopy structure analysis.

Q&As

In what clinical conditions might the measurement of SFTPB levels be relevant?

The measurement of SFTPB levels is relevant in conditions such as respiratory distress syndrome, interstitial lung diseases, and certain genetic disorders affecting surfactant production.

How does SFTPB research contribute to the development of novel drugs for respiratory diseases?

Research on SFTPB provides insights into the molecular mechanisms of lung function, facilitating the development of targeted drugs to address surfactant deficiencies.

Are there any advancements in diagnostic technologies that enhance the detection of SFTPB abnormalities?

Advancements in genetic testing and imaging technologies have improved the accuracy and efficiency of detecting SFTPB abnormalities, aiding in early diagnosis.

Can mutations in the SFTPB gene contribute to respiratory diseases?

Yes, mutations in the SFTPB gene can lead to dysfunctional SFTPB protein, contributing to various respiratory diseases.

How is the clinical diagnosis of SFTPB-related disorders typically conducted?

Clinical diagnosis involves assessing respiratory symptoms, conducting imaging studies, and performing genetic testing to identify mutations in the SFTPB gene.