Recombinant Human SHISA3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SHISA3-1853H
• Product Overview: SHISA3 MS Standard C13 and N15-labeled recombinant protein (NP_001073974) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a single-transmembrane protein which is one of nine members of a family of transmembrane adaptors that modulate both WNT and FGF signaling by blocking the maturation and transport of their receptors to the cell surface. Members of this family contain an N-terminal cysteine-rich domain with a distinct cysteine pattern, a single transmembrane domain, and a C-terminal proline-rich, low complexity region. The encoded protein acts as a tumor suppressor by accelerating beta-catenin degradation.
• Molecular Mass: 25.7 kDa
• AA Sequence: MRALLALCLLLGCLRWGPAGAQQSGEYCHGWVDVQGNYHEGFQCPEDFDTLDATICCGSCALRYCCAAADARLEQGGCTNDRRELEHPGITAQPVYVPFLIVGSIFIAFIILGSVVAIYCCTCLRPKEPSQQPIRFSLRSYQTETLPMILTSTSPRAPSRQSSTATSSSSTGGSIRRFSFARAEPGCLVPSPPPPYTTSHSIHLAQPSGFLVSPQYFAYPLQQEPPLPGKSCPDFSSSTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SHISA3 shisa family member 3 [ Homo sapiens (human) ]
• Official Symbol: SHISA3
• Synonyms: SHISA3; shisa homolog 3 (Xenopus laevis); protein shisa-3 homolog; hShisa3
• Gene ID: 152573
• mRNA Refseq: NM_001080505
• Protein Refseq: NP_001073974
• MIM: 617325
• UniProt ID: A0PJX4