Recombinant Human SHOC2 protein, GST-tagged

• Cat.No.: SHOC2-2664H
• Product Overview: Recombinant Human SHOC2(1 a.a. - 582 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Protein Length: 1-582 a.a.
• Description: This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair.
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 89.76 kDa
• AA Sequence: MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRP NPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIEELTQLTELYLYSNKLQSLPAEVGCLVNLMT LALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIREN KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIP RSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIF SRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKL RELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLN DNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: SHOC2 SHOC2 leucine-rich repeat scaffold protein [ Homo sapiens ]
• Official Symbol: SHOC2
• Synonyms: SOC2; SUR8; SIAA0862; soc-2 suppressor of clear homolog
• Gene ID: 8036
• mRNA Refseq: NM_007373
• Protein Refseq: NP_031399
• MIM: 602775
• UniProt ID: Q9UQ13
• Chromosome Location: 10q25
• Pathway: EGFR1 Signaling Pathway, organism-specific biosystem
• Function: protein phosphatase binding; protein phosphatase regulator activity