Recombinant Human signal sequence receptor, delta, His-tagged

• Cat.No.: SSR4-382H
• Product Overview: SSR4, 24-144aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 24-144 a.a.
• Description: SSR4 is the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants. Recombinant human SSR4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• Molecular Mass: 16.1 kDa (144aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSEACLEPQ ITPSYYTTSD AVISTETVFI VEISLTCKNR VQNMALYADV GGKQFPVTRG QDVGRYQVSW SLDHKSAHAG TYEVRFFDEE SYSLLRKAQR NNEDISIIPP LFTVSVDHRG TWNG
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: SSR4 signal sequence receptor, delta [ Homo sapiens ]
• Official Symbol: SSR4
• Synonyms: SSR4; signal sequence receptor, delta; translocon-associated protein subunit delta; translocon associated protein delta; TRAPD; SSR-delta; TRAP-delta; translocon-associated protein delta; signal sequence receptor subunit delta
• Gene ID: 6748
• mRNA Refseq: NM_001204526
• Protein Refseq: NP_001191455
• MIM: 300090
• UniProt ID: P51571
• Chromosome Location: Xq28
• Pathway: Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem; Translation, organism-specific biosystem; Translocon-associated protein (TRAP) complex, organism-specific biosystem
• Function: calcium ion binding