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Recombinant Human SLAMF8 Protein, His-tagged

Cat.No. : SLAMF8-726H
Product Overview : Recombinant Human SLAMF8(Ala23-Asp233) fused with His tag at the C-terminus was produced in HEK293.
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Description : SLAM family member 8(SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF8 encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. The protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment.
Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Protein length : Ala23-Asp233
AA sequence : AQVLSKVGGSVLLVAARPPGFQVRE AIWRSLWPSEELLATFFRGSLETLY HSRFLGRAQLHSNLS LELGPLESGDSGNFSVLMVDTRGQP WTQTLQLKVYDAVPRPVVQVFIAVE RDAQPSKTCQVFLSC WAPNISEITYSWRRETTMDFGMEPH SLFTDGQVLSISLGPGDRDVAYSCI VSNPVSWDLATVTPW DSCHHEAAPGKASYKDVDHHHHHH
Endotoxin : Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Storage : Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
Reconstitution : Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Shipping : The product is shipped at ambient temperature.
Gene Name : SLAMF8 SLAM family member 8 [ Homo sapiens ]
Official Symbol : SLAMF8
Synonyms : SLAMF8; SLAM family member 8; BLAME; CD353; SBBI42; BCM-like membrane protein; B lymphocyte activator macrophage expressed; B-lymphocyte activator macrophage expressed; FLJ20442; MGC129578;
Gene ID : 56833
mRNA Refseq : NM_020125
Protein Refseq : NP_064510
MIM : 606620
UniProt ID : Q9P0V8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How is SLAMF8 implicated in inflammatory and autoimmune conditions? 01/23/2022

Dysregulation of SLAMF8 can contribute to inflammatory and autoimmune diseases.

Are there potential therapeutic interventions targeting SLAMF8? 03/15/2021

Therapeutic interventions could potentially target SLAMF8 to modulate immune responses in various diseases.

What role does SLAMF8 play in the regulation of immune responses? 03/01/2021

It acts as an inhibitory receptor, modulating immune cell activation and cytokine production.

What are the molecular mechanisms governing SLAMF8 activity? 06/27/2020

SLAMF8 activity is governed by interactions with other cell surface receptors and intracellular signaling pathways.

In which immune cells is SLAMF8 predominantly expressed? 02/09/2020

SLAMF8 is predominantly found in myeloid cells, like macrophages and dendritic cells.

What is the primary function of SLAMF8 in the immune system? 11/14/2019

SLAMF8 regulates immune responses, particularly in myeloid cells.

How does SLAMF8 contribute to immune cell signaling? 08/27/2019

It participates in cell-cell signaling, influencing immune cell activation and function.

Customer Reviews (3)

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Reviews
10/19/2021

    Perfect for biological assays.

    03/03/2021

      Product works as expected.

      06/20/2020

        Very reliable, worth the price.

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