Recombinant Human SLAMF8 Protein, His-tagged
Cat.No. : | SLAMF8-726H |
Product Overview : | Recombinant Human SLAMF8(Ala23-Asp233) fused with His tag at the C-terminus was produced in HEK293. |
- Specification
- Gene Information
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Description : | SLAM family member 8(SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF8 encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. The protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Protein length : | Ala23-Asp233 |
AA sequence : | AQVLSKVGGSVLLVAARPPGFQVRE AIWRSLWPSEELLATFFRGSLETLY HSRFLGRAQLHSNLS LELGPLESGDSGNFSVLMVDTRGQP WTQTLQLKVYDAVPRPVVQVFIAVE RDAQPSKTCQVFLSC WAPNISEITYSWRRETTMDFGMEPH SLFTDGQVLSISLGPGDRDVAYSCI VSNPVSWDLATVTPW DSCHHEAAPGKASYKDVDHHHHHH |
Endotoxin : | Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
Purity : | Greater than 95% as determined by reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | SLAMF8 SLAM family member 8 [ Homo sapiens ] |
Official Symbol : | SLAMF8 |
Synonyms : | SLAMF8; SLAM family member 8; BLAME; CD353; SBBI42; BCM-like membrane protein; B lymphocyte activator macrophage expressed; B-lymphocyte activator macrophage expressed; FLJ20442; MGC129578; |
Gene ID : | 56833 |
mRNA Refseq : | NM_020125 |
Protein Refseq : | NP_064510 |
MIM : | 606620 |
UniProt ID : | Q9P0V8 |
Products Types
◆ Recombinant Protein | ||
Slamf8-4063M | Recombinant Mouse Slamf8 protein(Met1-Asp231), His-tagged | +Inquiry |
SLAMF8-4063H | Recombinant Human SLAMF8 Protein, His (Fc)-Avi-tagged | +Inquiry |
SLAMF8-120H | Recombinant Human SLAMF8 Protein, C-His-tagged | +Inquiry |
Slamf8-5899M | Recombinant Mouse Slamf8 Protein, Myc/DDK-tagged | +Inquiry |
SLAMF8-1776R | Recombinant Rhesus Monkey SLAMF8 Protein | +Inquiry |
◆ Lysates | ||
SLAMF8-2093MCL | Recombinant Mouse SLAMF8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDysregulation of SLAMF8 can contribute to inflammatory and autoimmune diseases.
Therapeutic interventions could potentially target SLAMF8 to modulate immune responses in various diseases.
It acts as an inhibitory receptor, modulating immune cell activation and cytokine production.
SLAMF8 activity is governed by interactions with other cell surface receptors and intracellular signaling pathways.
SLAMF8 is predominantly found in myeloid cells, like macrophages and dendritic cells.
SLAMF8 regulates immune responses, particularly in myeloid cells.
It participates in cell-cell signaling, influencing immune cell activation and function.
Customer Reviews (3)
Write a reviewPerfect for biological assays.
Product works as expected.
Very reliable, worth the price.
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