Recombinant Human SLC11A2 Protein (V2-R568), 8×His-MBP, Flag tagged

• Cat.No.: SLC11A2-0560H
• Product Overview: Recombinant Human 8His-MBP-TEV-(GG)-SLC11A2(V2-R568)-Flag Protein was expressed in Insect cell.

Specification

• Description: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
• Source: Insect cell
• Species: Human
• Tag: 8His-MBP,Flag
• Form: Liquid
• Protein Length: V2-R568
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 [ Homo sapiens (human) ]
• Official Symbol: SLC11A2
• Synonyms: SLC11A2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; NRAMP2; natural resistance-associated macrophage protein 2; DCT1; DMT1; DMT-1; NRAMP 2; divalent cation transporter 1; FLJ37416
• Gene ID: 4891
• mRNA Refseq: NM_000617
• Protein Refseq: NP_000608
• MIM: 600523
• UniProt ID: P49281