Recombinant Human SLC13A3 Protein, GST-tagged

• Cat.No.: SLC13A3-672H
• Product Overview: Recombinant Human SLC13A3 Full-Length ORF Protein (1-602 aa) is produced by Wheat Germ (in vitro) expression system. This protein is fused with a GST tag at the N-terminal.

Specification

• Description: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role
  in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the Full-Length nature of some of them have not been characterized yet.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 93.2 kDa
• Protein length: 1-602 aa
• AA Sequence: MAALAAAAKKVWSARRLLVLLFTPL ALLPVVFALPPKEGRCLFVILLMAV YWCTEALPLSVTALLPIVLFPFMGI LPSNKVCPQYFLDTNFLFLSGLIMA SAIEEWNLHRRIALKILMLVGVQPA RLILGMMVTTSFLSMWLSNTASTAM MLPIANAILKSLFGQKEVRKDPSQE SEENTAAVRRNGLHTVPTEMQFLAS TEAKDHPGETEVPLDLPADSRKEDE YRRNIWKGFLISIPYSASIGGTATL TGTAPNLILLGQLKSFFPQCDVVNF GSWFIFAFPLMLLFLLAGWLWISFL YGGLSFRGWRKNKSEIRTNAEDRAR AVIREEYQNLGPIKFAEQAVFILFC MFAILLFTRDPKFIPGWASLFNPGF LSDAVTGVAIVTILFFFPSQRPSLK WWFDFKAPNTETEPLLTWKKAQETV PWNIILLLGGGFAMAKGCEESGLSV WIGGQLHPLENVPPALAVLLITVVI AFFTEFASNTATIIIFLPVLAELAI RLRVHPLYLMIPGTVGCSFAFMLPV STPPNSIAFASGHLLVKDMVRTGLL MNLMGVLLLSLAMNTWAQTIFQLGT FPDWADMYSVNVTALPPTLANDTFR TL
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 [ Homo sapiens ]
• Official Symbol: SLC13A3
• Synonyms: SLC13A3; NADC3; SDCT2; hNaDC3; naDC-3
• Gene ID: 64849
• mRNA Refseq: NM_001011554
• Protein Refseq: NP_001011554
• MIM: 606411
• UniProt ID: Q8WWT9