Recombinant Human SLC18A2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SLC18A2-3812H
• Product Overview: SLC18A2 MS Standard C13 and N15-labeled recombinant protein (NP_003045) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 55.5 kDa
• AA Sequence: MALSELALVRWLQESRRSRKLILFI VFLALLLDNMLLTVVVPIIPSYLYS IKHEKNATEIQTARPVHTASISDSF QSIFSYYDNSTMVTGNATRDLTLHQ TATQHMVTNASAVPSDCPSEDKDLL NENVQVGLLFASKATVQLITNPFIG LLTNRIGYPIPIFAGFCIMFVSTIM FAFSSSYAFLLIARSLQGIGSSCSS VAGMGMLASVYTDDEERGNVMGIAL GGLAMGVLVGPPFGSVLYEFVGKTA PFLVLAALVLLDGAIQLFVLQPSRV QPESQKGTPLTTLLKDPYILIAAGS ICFANMGIAMLEPALPIWMMETMCS RKWQLGVAFLPASISYLIGTNIFGI LAHKMGRWLCALLGMIIVGVSILCI PFAKNIYGLIAPNFGVGFAIGMVDS SMMPIMGYLVDLRHVSVYGSVYAIA DVAFCMGYAIGPSAGGAIAKAIGFP WLMTIIGIIDILFAPLCFFLRSPPA KEEKMAILMDHNCPIKTKMYTQNNI QSYPIGEDEESESDSGPTRTRRLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SLC18A2 solute carrier family 18 member A2 [ Homo sapiens (human) ]
• Official Symbol: SLC18A2
• Synonyms: SLC18A2; solute carrier family 18 (vesicular monoamine), member 2; VMAT2; synaptic vesicular amine transporter; SVAT; SVMT; monoamine transporter; vesicular amine transporter 2; vesicle monoamine/H+ antiporter; solute carrier family 18 member 2; vesicle monoamine transporter type 2; monoamine neurotransmitter transporter; VAT2; MGC26538; MGC120477; MGC120478
• Gene ID: 6571
• mRNA Refseq: NM_003054
• Protein Refseq: NP_003045
• MIM: 193001
• UniProt ID: Q05940