Recombinant Human SLC1A2 Protein, His-tagged

• Cat.No.: SLC1A2-2060H
• Product Overview: Recombinant Human SLC1A2 Protein (Met1-Asn44) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 8.7 kDa
  Accurate Molecular Mass: 9 kDa
• Protein length: Met1-Asn44
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: SLC1A2 solute carrier family 1 member 2 [ Homo sapiens (human) ]
• Official Symbol: SLC1A2
• Synonyms: Slc1a2; solute carrier family 1 member 2; Glt; Eaat2; Glt-1; excitatory amino acid transporter 2; glial glutamate transporter GLT1/V3; glial glutamate transporter GLT1/V4; glutamate transporter 1; high affinity glucose transporter; sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2
• Gene ID: 6506
• mRNA Refseq: NM_004171
• Protein Refseq: NP_004162
• MIM: 600300
• UniProt ID: P43004