Recombinant Human SLC26A4 protein, GST-tagged
Cat.No. : | SLC26A4-317H |
Product Overview : | Recombinant Human SLC26A4(1 a.a. - 780 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 112.75 kDa |
Protein length : | 1 a.a. - 780 a.a. |
AA Sequence : | MAAPGGRSEPPQLPEYSCSYMVSRP VYSELAFQQQHERRLQERKTLRESL AKCCSCSRKRAFGVLKTLVPILEWL PKYRVKEWLLSDVISGVSTGLVATL QGMAYALLAAVPVGYGLYSAFFPIL TYFIFGTSRHISVGPFPVVSLMVGS VVLSMAPDEHFLVSSSNGTVLNTTM IDTAARDTARVLIASALTLLVGIIQ LIFGGLQIGFIVRYLADPLVGGFTT AAAFQVLVSQLKIVLNVSTKNYNGV LSIIYTLVEIFQNIGDTNLADFTAG LLTIVVCMAVKELNDRFRHKIPVPI PIEVIVTIIATAISYGANLEKNYNA GIVKSIPRGFLPPELPPVSLFSEML AASFSIAVVAYAIAVSVGKVYATKY DYTIDGNQEFIAFGISNIFSGFFSC FVATTALSRTAVQESTGGKTQVAGI ISAAIVMIAILALGKLLEPLQKSVL AAVVIANLKGMFMQLCDIPRLWRQN KIDAVIWVFTCIVSIILGLDLGLLA GLIFGLLTVVLRVQFPSWNGLGSIP STDIYKSTKNYKNIEEPQGVKILRF SSPIFYGNVDGFKKCIKSTVGFDAI RVYNKRLKALRKIQKLIKSGQLRAT KNGIISDAVSTNNAFEPDEDIEDLE ELDIPTKEIEIQVDWNSELPVKVNV PKVPIHSLVLDCGAISFLDVVGVRS LRVIVKEFQRIDVNVYFASLQDYVI EKLEQCGFFDDNIRKDTFFLTVHDA ILYLQNQVKSQEGQGSILETITLIQ DCKDTLELIETELTEEELDVQDEAM RTLAS |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | SLC26A4 solute carrier family 26, member 4 [ Homo sapiens ] |
Official Symbol : | SLC26A4 |
Synonyms : | SLC26A4; solute carrier family 26, member 4; DFNB4; pendrin; PDS; sodium-independent chloride/iodide transporter; EVA; TDH2B; |
Gene ID : | 5172 |
mRNA Refseq : | NM_000441 |
Protein Refseq : | NP_000432 |
MIM : | 605646 |
UniProt ID : | O43511 |
Chromosome Location : | 7q31 |
Pathway : | Multifunctional anion exchangers, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of inorganic cations/anions and amino acids/oligopeptides, organism-specific biosystem; |
Function : | chloride transmembrane transporter activity; iodide transmembrane transporter activity; secondary active sulfate transmembrane transporter activity; sulfate transmembrane transporter activity; transporter activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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