| Description : |
Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
85.5 kDa |
| AA Sequence : |
MAAPGGRSEPPQLPEYSCSYMVSRP VYSELAFQQQHERRLQERKTLRESL AKCCSCSRKRAFGVLKTLVPILEWL PKYRVKEWLLSDVISGVSTGLVATL QGMAYALLAAVPVGYGLYSAFFPIL TYFIFGTSRHISVGPFPVVSLMVGS VVLSMAPDEHFLVSSSNGTVLNTTM IDTAARDTARVLIASALTLLVGIIQ LIFGGLQIGFIVRYLADPLVGGFTT AAAFQVLVSQLKIVLNVSTKNYNGV LSIIYTLVEIFQNIGDTNLADFTAG LLTIVVCMAVKELNDRFRHKIPVPI PIEVIVTIIATAISYGANLEKNYNA GIVKSIPRGFLPPELPPVSLFSEML AASFSIAVVAYAIAVSVGKVYATKY DYTIDGNQEFIAFGISNIFSGFFSC FVATTALSRTAVQESTGGKTQVAGI ISAAIVMIAILALGKLLEPLQKSVL AAVVIANLKGMFMQLCDIPRLWRQN KIDAVIWVFTCIVSIILGLDLGLLA GLIFGLLTVVLRVQFPSWNGLGSIP STDIYKSTKNYKNIEEPQGVKILRF SSPIFYGNVDGFKKCIKSTVGFDAI RVYNKRLKALRKIQKLIKSGQLRAT KNGIISDAVSTNNAFEPDEDIEDLE ELDIPTKEIEIQVDWNSELPVKVNV PKVPIHSLVLDCGAISFLDVVGVRS LRVIVKEFQRIDVNVYFASLQDYVI EKLEQCGFFDDNIRKDTFFLTVHDA ILYLQNQVKSQEGQGSILETITLIQ DCKDTLELIETELTEEELDVQDEAM RTLASTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
