Recombinant Human SLC2A4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SLC2A4-2171H
• Product Overview: SLC2A4 MS Standard C13 and N15-labeled recombinant protein (NP_001033) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 54.6 kDa
• AA Sequence: MPSGFQQIGSEDGEPPQQRVTGTLV LAVFSAVLGSLQFGYNIGVINAPQK VIEQSYNETWLGRQGPEGPSSIPPG TLTTLWALSVAIFSVGGMISSFLIG IISQWLGRKRAMLVNNVLAVLGGSL MGLANAAASYEMLILGRFLIGAYSG LTSGLVPMYVGEIAPTHLRGALGTL NQLAIVIGILIAQVLGLESLLGTAS LWPLLLGLTVLPALLQLVLLPFCPE SPRYLYIIQNLEGPARKSLKRLTGW ADVSGVLAELKDEKRKLERERPLSL LQLLGSRTHRQPLIIAVVLQLSQQL SGINAVFYYSTSIFETAGVGQPAYA TIGAGVVNTVFTLVSVLLVERAGRR TLHLLGLAGMCGCAILMTVALLLLE RVPAMSYVSIVAIFGFVAFFEIGPG PIPWFIVAELFSQGPRPAAMAVAGF SNWTSNFIIGMGFQYVAEAMGPYVF LLFAVLLLGFFIFTFLRVPETRGRT FDQISAAFHRTPSLLEQEVKPSTEL EYLGPDENDTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SLC2A4 solute carrier family 2 member 4 [ Homo sapiens (human) ]
• Official Symbol: SLC2A4
• Synonyms: SLC2A4; solute carrier family 2 (facilitated glucose transporter), member 4; GLUT4; solute carrier family 2, facilitated glucose transporter member 4; GLUT-4; insulin-responsive glucose transporter type 4; glucose transporter type 4, insulin-responsive
• Gene ID: 6517
• mRNA Refseq: NM_001042
• Protein Refseq: NP_001033
• MIM: 138190
• UniProt ID: P14672