Recombinant Human SLC39A8 Protein, GST-tagged

• Cat.No.: SLC39A8-671H
• Product Overview: Recombinant Human SLC39A8 Full-Length ORF Protein (1-460 aa) is produced by Wheat Germ (in vitro) expression system. This protein is fused with a GST tag at the N-terminal.

Specification

• Description: This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their Full-Length nature is not known.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 76 kDa
• Protein length: 1-460 aa
• AA Sequence: MAPGRAVAGLLLLAAAGLGGVAEGP GLAFSEDVLSVFGANLSLSAAQLQH LLEQMGAASRVGVPEPGQLHFNQCL TAEEIFSLHGFSNATQITSSKFSVI CPAVLQQLNFHPCEDRPKHKTRPSH SEVWGYGFLSVTIINLASLLGLILT PLIKKSYFPKILTFFVGLAIGTLFS NAIFQLIPEAFGFDPKVDSYVEKAV AVFGGFYLLFFFERMLKMLLKTYGQ NGHTHFGNDNFGPQEKTHQPKALPA INGVTCYANPAVTEANGHIHFDNVS VVSLQDGKKEPSSCTCLKGPKLSEI GTIAWMITLCDALHNFIDGLAIGAS CTLSLLQGLSTSIAILCEEFPHELG DFVILLNAGMSTRQALLFNFLSACS CYVGLAFGILVGNNFAPNIIFALAG GMFLYISLADMFPEMNDMLREKVTG RKTDFTFFMIQNAGMLTGFTAILLI TLYAGEIELE
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: SLC39A8 solute carrier family 39 (zinc transporter), member 8 [ Homo sapiens ]
• Official Symbol: SLC39A8
• Synonyms: SLC39A8; BIGM103; ZIP-8; ZIP8; PP3105; LZT-Hs6
• Gene ID: 64116
• mRNA Refseq: NM_001135146
• Protein Refseq: NP_001128618
• MIM: 608732
• UniProt ID: Q9C0K1