| Description : |
This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
117.6 kDa |
| AA Sequence : |
MNLFNLDRFRFEKRNKIEEAPEATP QPSQPGPSSPISLSAEEENAEGEVS RANTPDSDITEKTEDSSVPETPDNE RKASISYFKNQRGIQYIDLSSDSED VVSPNCSNTVQEKTFNKDTVIIVSE PSEDEESQGLPTMARRNDDISELED LSELEDLKDAKLQTLKELFPQRSDN DLLKLIESTSTMDGAIAAALLMFGD AGGGPRKRKLSSSSEPYEEDEFNDD QSIKKTRLDHGEESNESAESSNNWE KQESIVLKLQKEFPNFDKQELREVL KEHEWMYTEALESLKVFAEDQDMQY ASQSEVPNGKEVSSRSQNYPKNATK TKLKQKFSMKAQNGFNKKRKKNVFN QKRVVEDSEYDSGSDVGSSLDEDYS SGEEVMEDGYKGKILHFLQDASIGE LTLIPQCSQKKAQKITELRPFNSWE ALFTKMSKTNGLSEDLIWHCKTLIQ ERDVVIRLMNKCEDISNKLTKQVTM LTGNGGGWNIEQPSILNQSLSLKPY QKVGLNWLALVHKHGLNGILADEMG LGKTIQAIAFLAYLYQEGNNGPHLI VVPASTIDNWLREVNLWCPTLKVLC YYGSQEERKQIRFNIHSRYEDYNVI VTTYNCAISSSDDRSLFRRLKLNYA IFDEGHMLKNMGSIRYQHLMTINAN NRLLLTGTPVQNNLLELMSLLNFVM PHMFSSSTSEIRRMFSSKTKSADEQ SIYEKERIAHAKQIIKPFILRRVKE EVLKQLPPKKDRIELCAMSEKQEQL YLGLFNRLKKSINNLVTEKNTEMCN VMMQLRKMANHPLLHRQYYTAEKLK EMSQLMLKEPTHCEANPDLIFEDME VMTDFELHVLCKQYRHINNFQLDMD LILDSGKFRVLGCILSELKQKGDRV VLFSQFTMMLDILEVLLKHHQHRYL RLDGKTQISERIHLIDEFNTDMDIF VFLLSTKAGGLGINLTSANVVILHD IDCNPYNDKQAEDRCHRVGQTKEAL VIKLISQGTIEESMLKINQQKLKLE QDMTTVDEGDEGSMPADIATLLKTS MGLTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
