Recombinant Human SMS Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SMS-5827H
• Product Overview: SMS MS Standard C13 and N15-labeled recombinant protein (NP_004586) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 41.3 kDa
• AA Sequence: MAAARHSTLDFMLGAKADGETILKG LQSIFQEQGMAESVHTWQDHGYLAT YTNKNGSFANLRIYPHGLVLLDLQS YDGDAQGKEEIDSILNKVEERMKEL SQDSTGRVKRLPPIVRGGAIDRYWP TADGRLVEYDIDEVVYDEDSPYQNI KILHSKQFGNILILSGDVNLAESDL AYTRAIMGSGKEDYTGKDVLILGGG DGGILCEIVKLKPKMVTMVEIDQMV IDGCKKYMRKTCGDVLDNLKGDCYQ VLIEDCIPVLKRYAKEGREFDYVIN DLTAVPISTSPEEDSTWEFLRLILD LSMKVLKQDGKYFTQGNCVNLTEAL SLYEEQLGRLYCPVEFSKEIVCVPS YLELWVFYTVWKKAKPTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SMS spermine synthase [ Homo sapiens (human) ]
• Official Symbol: SMS
• Synonyms: SMS; spermine synthase; Snyder Robinson X linked mental retardation syndrome, SRS; MRSR; SPMSY; SpS; spermidine aminopropyltransferase; Snyder-Robinson X-linked mental retardation syndrome; SRS
• Gene ID: 6611
• mRNA Refseq: NM_004595
• Protein Refseq: NP_004586
• MIM: 300105
• UniProt ID: P52788