Recombinant Human SMYD1 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: SMYD1-076H
• Product Overview: SMYD1 MS Standard C13 and N15-labeled recombinant protein (NP_938015) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 56.6 kDa
• AA Sequence: MTIGRMENVEVFTAEGKGRGLKATK EFWAADIIFAERAYSAVVFDSLVNF VCHTCFKRQEKLHRCGQCKFAHYCD RTCQKDAWLNHKNECSAIKRYGKVP NENIRLAARIMWRVEREGTGLTEGC LVSVDDLQNHVEHFGEEEQKDLRVD VDTFLQYWPPQSQQFSMQYISHIFG VINCNGFTLSDQRGLQAVGVGIFPN LGLVNHDCWPNCTVIFNNGNHEAVK SMFHTQMRIELRALGKISEGEELTV SYIDFLNVSEERKRQLKKQYYFDCT CEHCQKKLKDDLFLGVKDNPKPSQE VVKEMIQFSKDTLEKIDKARSEGLY HEVVKLCRECLEKQEPVFADTNIYM LRMLSIVSEVLSYLQAFEEASFYAR RMVDGYMKLYHPNNAQLGMAVMRAG LTNWHAGNIEVGHGMICKAYAILLV THGPSHPITKDLEAMRVQTEMELRM FRQNEFMYYKMREAALNNQPMQVMA EPSNEPSPALFHKKQTRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SMYD1 SET and MYND domain containing 1 [ Homo sapiens (human) ]
• Official Symbol: SMYD1
• Synonyms: SMYD1; SET and MYND domain containing 1; BOP; KMT3D; ZMYND18; ZMYND22; histone-lysine N-methyltransferase SMYD1; CD8 beta opposite; SET and MYND domain-containing protein 1; zinc finger, MYND domain containing 18; EC 2.1.1.354
• Gene ID: 150572
• mRNA Refseq: NM_198274
• Protein Refseq: NP_938015
• MIM: 606846
• UniProt ID: Q8NB12