Recombinant Human SNAPIN Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SNAPIN-3210H
• Product Overview: SNAPIN MS Standard C13 and N15-labeled recombinant protein (NP_036569) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 14.9 kDa
• AA Sequence: MAGAGSAAVSGAGTPVAGPTGRDLFAEGLLEFLRPAVQQLDSHVHAVRESQVELREQIDNLATELCRINEDQKVALDLDPYVKKLLNARRRVVLVNNILQNAQERLRRLNHSVAKETARRRAMLDSGIYPPGSPGKSGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SNAPIN SNAP-associated protein [ Homo sapiens (human) ]
• Official Symbol: SNAPIN
• Synonyms: SNAPIN; SNAP-associated protein; SNAPAP; SNARE-associated protein Snapin; SNAP 25 binding protein; snapin; SNAP-25-binding protein; SNARE associated protein snapin; synaptosomal-associated protein 25-binding protein
• Gene ID: 23557
• mRNA Refseq: NM_012437
• Protein Refseq: NP_036569
• MIM: 607007
• UniProt ID: O95295