Recombinant Human SNCA Protein

• Cat.No.: SNCA-385H
• Product Overview: Recombinant Human SNCA(1-140 aa) was expressed in E. coli.

Specification

• Description: SNCA is associated with human neurodegenerative diseases, where it forms aggregates in nerve tissues. Diseases include Parkinson’s disease, dementia with lewy bodies, and multi-system atrophy, but also other’s disease like Alzheimer’s Disease. Lewy Bodies are well-known cytoplasmic deposits of SNCA in Parkinson’s disease.
• Source: E. coli
• Species: Human
• Form: Finally dialysed in pure water, shock frozen in liquid nitrogen at a protein concentration of 2.5 mg/ml
• Molecular Mass: 14604 kg/mol
• Protein length: 1-140 aa
• AA Sequence: GSMDVFMKGLSKAKEGVVAAAEKTK QGVAEAAGKTKEGVLYVGSKTKEGV VHGVATVAEKTKEQVTNVGGAVVTG VTAVAQKTVEGAGSIAAATGFVKKD QLGKNEEGAPQEGILEDMPVDPDNE AYEMPSEEGYQDYEPEA
• Purity: > 98% by SDS-PAGE
• Notes: Thawing: Gentle agitation at 37 centigrade. Refreezing is not recommended and should be avoided.
• Storage: Store at -80 centigrade
• Concentration: 2.5 mg/ml

Gene Information

• Gene Name: SNCA synuclein, alpha (non A4 component of amyloid precursor) [ Homo sapiens ]
• Official Symbol: SNCA
• Synonyms: SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC110988
• Gene ID: 6622
• mRNA Refseq: NM_000345
• Protein Refseq: NP_000336
• MIM: 163890
• UniProt ID: P37840