Recombinant Human SOD1

• Cat.No.: SOD1-30341TH
• Product Overview: Recombinant full length Human Superoxide Dismutase 1 with N-terminal proprietary tag; amino acids 1-54, MW 45kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 1-54 a.a.
• Description: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the Cu-Zn superoxide dismutase family.
• Full Length: Full L.

Gene Information

• Gene Name: SOD1 superoxide dismutase 1, soluble [ Homo sapiens ]
• Official Symbol: SOD1
• Synonyms: SOD1; superoxide dismutase 1, soluble; ALS, ALS1, amyotrophic lateral sclerosis 1 (adult); superoxide dismutase [Cu-Zn]; IPOA
• Gene ID: 6647
• mRNA Refseq: NM_000454
• Protein Refseq: NP_000445
• MIM: 147450
• Uniprot ID: P00441
• Chromosome Location: 21q22.11
• Pathway: Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: chaperone binding; copper ion binding; metal ion binding; oxidoreductase activity; protein binding