Recombinant Human soluble tumor necrosis factor receptor superfamily, member 1B, His-tagged

• Cat.No.: TNFRSF1B-125H
• Product Overview: Recombinant Human sTNFR-II comprises a 184 amino acid fragment (23-206) corresponding to the mature sTNFR-II protein and is expressed in E. coli with an amino-terminal hexahistidine tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Two types of soluble TNF receptors (sTNFR-I and sTNFR-II) have been identified, which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women.
• Purity: >95% by SDS-PAGE
• Form: Liquid
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: TNFRSF1B tumor necrosis factor receptor superfamily, member 1B [ Homo sapiens ]
• Synonyms: Tumour necrosis factor receptor 2; Tumour receptor beta receptor; Tumour necrosis factor binding protein 2; Tumour necrosis factor receptor superfamily member 1B; Tumour necrosis factor receptor type II; p80 TNF alpha; receptor; Etanercept; CD120b; p75; TBPII; TNFRII, TNFR75; TNFBR; TNFR2; TNFR80; tumor necrosis factor receptor superfamily, member 1B; TNFRSF1B; TNFR1B; TNF-R75; p75TNFR; TNF-R-II; TNFRSF1B; p75 TNF receptor; OTTHUMP00000001784; soluble TNFR1B variant 1; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; TNF-R2; CD120b antigen.
• Gene ID: 7133
• mRNA Refseq: NM_001066
• Protein Refseq: NP_001057
• MIM: 191191
• UniProt ID: P20333
• Chromosome Location: 1p36.3-p36.2
• Function: protein binding; receptor activity; tumor necrosis factor receptor activity