Recombinant Human solute carrier family 5 member 12 Protein, His6ABP tagged

• Cat.No.: SLC5A12-23H
• Product Overview: Recombinant Human SLC5A12 Protein with N-His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G) tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: ABP&His
• Description: Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 in the distal proximal tubule.
• Tag: N-His&ABP
• Molecular Mass: 22 kDa including tags
• AA Sequence: QGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRH
• Purity: > 80% by SDS-PAGE and Coomassie blue staining
• Notes: Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
• Storage: Upon delivery store at -20 centigrade. Avoid repeated freeze/thaw cycles.
• Storage Buffer: PBS and 1M Urea, pH 7.4.
• Concentration: ≥0.5 mg/mL
• Shipping: Shipped in liquid form on wet ice.

Gene Information

• Gene Name: SLC5A12 solute carrier family 5 member 12 [ Homo sapiens (human) ]
• Official Symbol: SLC5A12
• Synonyms: SLC5A12; solute carrier family 5 (sodium/glucose cotransporter), member 12; sodium-coupled monocarboxylate transporter 2; MGC52019; solute carrier family 5 member 12; sodium-iodide related cotransporter; low-affinity sodium-lactate cotransporter; electroneutral sodium monocarboxylate cotransporter; SMCT2; DKFZp564G223
• Gene ID: 159963
• mRNA Refseq: NM_178498
• Protein Refseq: NP_848593
• MIM: 612455
• UniProt ID: Q1EHB4