Recombinant Human SOX10 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SOX10-2697H
• Product Overview: SOX10 MS Standard C13 and N15-labeled recombinant protein (NP_008872) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 49.9 kDa
• AA Sequence: MAEEQDLSEVELSPVGSEEPRCLSP GSAPSLGPDGGGGGSGLRASPGPGE LGKVKKEQQDGEADDDKFPVCIREA VSQVLSGYDWTLVPMPVRVNGASKS KPHVKRPMNAFMVWAQAARRKLADQ YPHLHNAELSKTLGKLWRLLNESDK RPFIEEAERLRMQHKKDHPDYKYQP RRRKNGKAAQGEAECPGGEAEQGGT AAIQAHYKSAHLDHRHPGEGSPMSD GNPEHPSGQSHGPPTPPTTPKTELQ SGKADPKRDGRSMGEGGKPHIDFGN VDIGEISHEVMSNMETFDVAELDQY LPPNGHPGHVSSYSAAGYGLGSALA VASGHSAWISKPPGVALPTVSPPGV DAKAQVKTETAGPQGPPHYTDQPST SQIAYTSLSLPHYGSAFPSISRPQF DYSDHQPSGPYYGHSGQASGLYSAF SYMGPSQRPLYTAISDPSPSGPQSH SPTHWEQPVYTTLSRPTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SOX10 SRY-box transcription factor 10 [ Homo sapiens (human) ]
• Official Symbol: SOX10
• Synonyms: SOX10; SRY (sex determining region Y)-box 10; transcription factor SOX-10; DOM; dominant megacolon; mouse; human homolog of; WS2E; WS4; SRY-related HMG-box gene 10; dominant megacolon, mouse, human homolog of; PCWH; WS4C; MGC15649
• Gene ID: 6663
• mRNA Refseq: NM_006941
• Protein Refseq: NP_008872
• MIM: 602229
• UniProt ID: P56693